association between polymorphism igf-i gene exon 1 and growth traits in moghani sheep

in this study, 100 moghani sheep from breeding station located in jaafarabad, moghan were genotyped for exon 1 of igf-i gene, using pcr-sscp. different band patterns were obtained in this site gene that was studied. based on sscp patterns, three genotypes bc, bd and bb obtained with frequencies of 65%, 26% and 9%, respectively. the genotype frequencies had a significant deviation from hwe. in addition, significant associations were observed between bb, bd and bc genotypes and weaning weight, weight in six months, weight in nine months, average daily gain and kleiber ratio. no association of the genotypes with the birth weight and yearling weight traits were found. these association polymorphisms and growth traitsmay be applied in sheep breeding schemes as marker assisted selection (mas).